Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

HERPES SIMPLEX VIRUS IGG TYPE 1 AND TYPE 2 SPECIFIC ANTIBODIES

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2456         Geisinger Epic ID: 15000

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) or frozen specimen also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 7 days. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Interpretation guide:
Result Interpretation
Negative Indicates the absence of type-specific antibodies to HSV. A negative result generally indicates that the patient has not been infected but does not always rule out acute HSV infection. If clinical exposure is suspected, despite a negative finding, a second sample should be collected in 4-6 weeks.
Equivocal A second sample should be collected in 4-6 weeks.
Positive Indicates the presence of type-specific IgG antibodies to HSV and suggests previous exposure.
Additional information:
This assay is type specific and can differentiate between HSV-1 and HSV-2 infections. A single positive result only indicates previous immunologic exposure. The test should be repeated in 4-6 weeks when negative or equivocal results are obtained in suspected early Herpes Simplex disease. The performance of this assay has not been established for pediatric or immunocompromised patients.
CPT code(s):
86695, 86696
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
HSV I IgG, HSV II IgG antibody detection.
Methodology:
Chemiluminescence
Synonyms:
HSV I & II IgG, HERPG
Type-specific Herpes IgG
Herpes simplex virus types I & II IgG
Herpes simplex virus antibody IgM
Clinical significance:
Herpes virus (HSV) serotypes 1 and 2 are closely related. HSV1 is more commonly associated with infections of non-genital sites, while HSV2 is associated with genital and neonatal infections.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Stacy Kenyon, PhD, DABCC
   
Review Date: 12/03/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Five days per week, 1st shift.
Performed stat? No
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