Dr. Yi Ding

Yi Ding, MD, PhDYi Ding, MD, PhD,
System and Core Laboratory Director of Molecular Diagnostics.

100 North Academy Avenue
Danville, PA 17822
1 800 695 6491

Dr. Ding is an associate of Geisinger Medical Laboratories at Danville, Pennsylvania, where she serves as the System and Core Laboratory Director of Molecular Diagnostics.

Education:

Dr. Ding received her MD from Beijing Medical University in Beijing, China, and her PhD at New York University School of Medicine.  She received pathology residency training at New York University Langone Medical Center, New York, New York, and completed fellowships in molecular genetic pathology at New York-Presbyterian Hospital, Weill Cornell Medical College, Cornell University, New York, New York, and in hematopathology at New York University Langone Medical Center, New York, New York.

Certifications:

Dr. Ding is board certified in both anatomic and clinical pathology, molecular genetic pathology, and hematology

Professional Affiliations:

Association for Molecular Pathology
New York State Society of Pathologists
College of American Pathologists
American Society for Clinical Pathology
United States and Canadian Academy of Pathology
Association of Chinese American Physician
Chinese American Pathologists Association
SIGMA Xi
American Association for the Advancement of Science
New York Academy of Sciences

Research Interests:

Hematopathology, molecular genetic pathology

Publications in Peer-Reviewed Journals:

Xu M, Pokrovskii M, Ding Y, Yi R, Au C, Harrison OJ, Galan C, Belkaid Y, Bonneau R, Littman DR. c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont. Nature. 2018;554(7692):373-377.

Ding Y, Miyamoto H, Rothberg PG. Is Tubulocystic Renal Cell Carcinoma Real?: Genomic Analysis Confirms the World Health Organization Classification. J Mol Diagn. 2018;20(1):28-30.

Reyes-Barron C, Burack WR, Rothberg PG, Ding Y. Next-Generation Sequencing for Minimal Residual Disease Surveillance in Acute Lymphoblastic Leukemia: An Update. Crit Rev Oncog. 2017;22(5-6):559-567.

Matsuzawa-Ishimoto Y, Shono Y, Gomez LE, Hubbard-Lucey VM, Cammer M, Neil J, Dewan MZ, Lieberman SR, Jay HV, Lazrak A, Liu C, Ding Y, van den Brink MRM, Cadwell K. Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.. J Exp Med . 2017;214(12):3687-3705.

Campisi L, Barbet G, Ding Y, Esplugues E, Flavell RA, Blander J. Apoptosis in response to microbial infection induces autoreactive T helper 17 cells. Nat Immunol. 2016;17(9):1084-1092.

Ramanan D, Bowcutt R, Lee SC, Tang MS, Kurtz ZD, Ding Y, Honda K, Gause W, Blaser MJ, Bonneau RA, Lim Y, Loke P, Cadwell K. Helminth infection promotes colonization resistance via type 2 immunity. Science. 2016;352(6285):608-612.

Kernbauer E, Ding Y, Cadwell K. An enteric viral Infection can functionally replace the beneficial cues provided by commensal bacteria. Nature. 2014;516:94098.

Singh M, Ding Y, Zhang LY, Song D, Gong Y, Ross DS, Wang JH, Grover S, Doval DC,Shao C, He ZL, He ZL, Chang V, Chin WW, Deng FM, Sing B, Zhang D, Xu RL, Lee P. Distinct breast cancer subtypes in women with early-onset disease across races. Am J Cancer Res.. 2014;4(4):337-352.

Ding Y, Cho M, Chan A, Gu P, Yao Y, Ziober A, Bai S. SALL4 is expressed in pancreatic acinar cell carcinoma. Case Rep Clin Pathol . 2014;1(2):36-41.

Xiong H, Maraver A, Latkowski J-A, Henderson T, Schlessinger K, Ding Y, Shen J, Tadokoro CE, Lafaille JJ. Characterization of two distinct lympho-proliferative diseases caused by ectopic expression of the notch ligand DLL4 on T cells. PLoS ONE. 2013;8(12):384841.

Ding Y, Chen L, Deng FM, Melamed J, Fan R, Bonsib S, Zhou M. Localized cystic disease of the kidney: distinction from cystic neoplasms and hereditary polycystic diseases. Am J Surg Pathol. 2013;37(4):5-6-513.

Marchiando AM, Ramanan D, Ding Y, Gomez1 LE, Hubbard-Lucey VM, Maurer K, Wang C, Ziel JW, van Rooijen N, Nuñez G, Finlay BB, Mysorekar IU, Cadwell K. A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. Cell Host Microbe. 2013;14(2):216-224.

Other Publications:

Ding Y, Wilson KS. Chronic Myeloid Leukemia. CAP/ACMG Cytogenetics Resource 2013;Continuing Education:CY-C.

Abstracts, Posters, and Other Presentations:

Campbell A, Crowe W, Spence J, Spence J, Rothberg P, Ding Y. Identification of FLT3 ITD using Next-Generation Sequencing (NGS): A single institution’s experience. Poster Association for Molecular Pathology (AMP) 2018, San Antonio, Texas, November 1-3, 2018.

Campbell A, Crowe W, Rothberg P, Ding Y.. Clinical Evaluation of the Archer VariantPlex Myeloid Panel for Mutation Profiling in Myeloid Neoplasms. Poster Association for Molecular Pathology (AMP) 2018, San Antonio, Texas, November 1-3, 2018.

Reyes-Barron C, Buscaglia B, Campbell A, Hicks D, Ding Y. Next Generation Sequencing for Quantitative Measurement of Human Epidermal Growth Factor Receptor-2 (HER2) Amplification: a Comparative Study. Poster Association for Molecular Pathology (AMP) 2018, San Antonio, Texas, November 1-3, 2018.

Reyes-Barron C, Campbell A, Rothberg P, Burack R, Ding Y. Next Generation Sequencing-Assays Detect B-Lymphocyte Clonality in Formalin-Fixed Paraffin Embedded Specimens of Classical Hodgkin Lymphoma without Microdissection. Poster Presentation USCAP 107th Annual Meeting, Vancouver, British Columbia, March 17-23, 2018.

Evans A, Ding Y, Laughlin T, Rothberg P, Casulo C, Burack R. IGH sequencing distinguishes multiple EBV+ Mucocutaneous ulcers (MCU) from recurrent malignant DLBCL. Platform Presentation Society of Hematopathology/European Association of Hematopathology Workshop meeting, Chicago, Illinois, September 7-9, 2017.

Crane GM, Rothberg P, Ding Y, Perkins AS, Liesveld JL, Burack R, and Evans AG. MDS/MonoMAC-like syndrome with multiple HPV-driven carcinomas arising in a patient with a novel germline GATA2 variant. Presentation Society of Hematopathology/European Association of Hematopathology Workshop meeting, Chicago, Illinois, September 7-9, 2017.

Ding Y, Crowe W, Spence J, Laughlin T, Spence J, Rothberg P, Burack WR. InDelDuper: a highly sensitive and specific algorithm for FLT3 ITD detection in next-generation. Platform Presentation USCAP 106th Annual Meeting, San Antonio, Texas, March 4-10, 2017.

Ding Y, Rothberg P, Laughlin T, Burack WR, and Evans AG. Multiple independent clonal origins of EBV+ lymphoproliferative disorders revealed by next generation deep sequencing of the immunoglobulin heavy chain (IGH) locus . Platform Presentation USCAP 106th Annual Meeting, San Antonio, Texas, March 4-10, 2017.

Ding Y, Kluk M, Fernandes H. Molecular profiles of discrete foci in multifocal invasive carcinomas: understanding intratumoral heterogeneity using NGS. Poster Association, Austin, Texas, November 5-7, 2015.

Ding Y, Navneet N, Rennert H, Fernandes. Assessment of cytology and needle core biopsies for detection of somatic mutations in lung cancer using next generation sequencing: concordance with surgical resection. Poster Association, Austin, Texas, November 5-7, 2015.

Ding Y, Zhang P, Fernandes H. Evaluation of a next generation sequencing panel for comprehensive mutation profiling of colorectal cancer. Poster Association, Austin, Texas, November 5-7, 2015.

Weidner A, Zhang P, Panarelli N, Ding Y, Rennert H, Yantiss R and Fernandes H. Somatic mutation profiles of MSI and MSS colorectal cancer identified by targeted next generation sequencing. Poster USCAP 104th Annual Meeting, Boston, Massachusetts, March 2015.

Ding Y, Zhou F, Yee-Chang M, Bannan M, Sun W, Wei X, Shi Y. Chronic diarrhea and multiple lung masses: unusual clinical presentations for medullary. Poster USCAP 102 nd Annual Meeting, Tampa, Florida, October 2014.

Ding Y, Yaskiv O, Chan T, Deng F, Melamed J, Zhou M. Low Grade Urothelial Carcinoma with Focal High Grade Component of the Urinary Bladder: Pathological Outcomes in Follow-Up Biopsies. Poster 102st Annual Meeting of United States and Canadian Academy of Pathology, Baltimore, Maryland, March 2013.

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