Dr. Guoli Chen

Dr. Guoli ChenGUOLI CHEN, MD, PhD
Anatomic and Clinical Pathology

100 North Academy Avenue
Danville, PA 17822-1920
1 800 695 6491

Dr. Chen is an Associate of Geisinger Medical Laboratories at Geisinger Medical Center in Danville, Pennsylvania.

 

 

Education:

Dr. Chen received his MD. from Jining Medical College, Jining, China. He also holds a PhD from Indiana University School of Medicine, Indianapolis, Indiana. He received his pathology residency training in anatomic and clinical pathology at Johns Hopkins University, Baltimore, Maryland, and completed a fellowship in Molecular Genetic Pathology and an elective rotation in Nephropathology at Johns Hopkins University.

Certifications:

Dr. Chen is board certified in anatomic and clinical pathology and molecular genetic pathology,

Professional Affiliations:

Association for Molecular Pathology (AMP)
United States and Canadian Academy of Pathology (USCAP)
College of American Pathologists (CAP)
American Society for Clinical Pathology (ASCP)
Chinese American Pathologists Association (CAPA)

Research Interests:

Renal pathology, gastrointestinal pathology, genitourinary pathology and molecular pathology.

Recent Academic Activity

Publications in Peer-Reviewed Journals:

Wriston DJ, Norfolk ER, Smith LM, Chen G, Bulbin DH. Doxycycline-induced antinuclear antibody and antineutrophil cytoplasmic antibody associated vasculitis: A case report and literature review. Case Rep Hheumatol. 2020; 2020:3853671-3853675.

Li H, Zhang Q, Shuman L, Kaag M, Raman JD2, Merrill S, DeGraff D, Warrick JI, Chen G. Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes. Sci Rep. 2020; 10(1):1439.

Yamashita H, Kawasawa YI, Shuman L, Zheng Z, Tran T, Walter V, Warrick, JI, Chen G, Al-Ahmadie H, Matthew Kaag, Wong PK, Raman JD, DeGraff DJ. Repression of transcription factor AP-2 Alpha by PPARr reveals a novel transcriptional circuit in basal-squamous bladder cancer. Oncogenesis. 2019; 8(12):69.

Ammar A, Zafar Ahmed Mahmood H, Shahid Z, Jain R, and Chen G. Etanercept-associated nephropathy.. Cureus. 2019; 11(8):e5419.

Merelo Alcocer V, Flamm A., Chen G, Helm K.. SOX10 immunostaining in granulomatous dermatoses and benign reactive lymph nodes. J Cutan Pathol. 2019; 46(8):586-590.

Warrick JI, Sjodahl G, Kaag MG, Raman JD, Merrill S, Shuman L, Chen G, Walter V, DeGraff DJ. Intratumoral Heterogeneity of Bladder Cancer by Molecular Subtypes and Histologic Variants. Eur Urol. 2019; 75(1):18-22.

Zein MSI, Chen G, Price H, Kaur G. Native Kidney BK Nephropathy – A case report. Clin Case Rep. 2019; 7(2):353-356.

Liu J, Han Z, Chen G, Li Y, Zhang J, Zheng G, Xu J, van Zijl PCM, Zhang S, Liu G. CEST MRI of sepsis-induced acute kidney injury. NMR Biomed. 2018; 31(8):e3942.

Chen G, Kaur G. Membranous or Membranous like GN - A case report of massive proteinuria, positive serum with negative PLA2R on biopsy. Clin Case Rep. 2018; 6:2198–2201.

Warrick JI, Kaag MG, Raman JD, Chan W, Tran T, Kunchala S, Shuman L, DeGraff DJ, Chen G. FOXA1 and CK14 as markers of luminal and basal subtypes in histologic variants of bladder cancer and their associated conventional urothelial carcinoma. Virchows Arch. 2017; 471:337-345.

Shah T, Kaag MG, Raman JD, Chen W, Tran T, Kunchala S, DeGraff DJ, Chen G, Warrick JI. Clinical significance of prominent retraction clefts in invasive urothelial carcinoma. Hum Pathol. 2017; 61:90-96.

Chen G, Yang Z, Eshleman JR, Netto GJ and Lin MT. Molecular diagnostics for precision medicine in colorectal cancer: current status and future perspective. Biomed Res Int. 2017; 2016:9850690.


Abstracts, Posters, and Other Presentations:

Zhang Q, Li H, Chen G, Yang Z. Reduced Expression of CDX2, CK20 and SATB2 in Mismatch Repair-Deficient Colorectal Carcinoma. Abstract College of American Pathologists, Held virtually, October 10-14, 2020.

Li H, Zhang Q, Shuman L, Kaag M, Raman JD2, Merrill S, DeGraff D, Warrick JI, Chen G. Immune Profiles of Invasive Urothelial Carcinoma post Neoadjuvant Therapy and in Positive Lymph Nodes: Parts of the PDL1 Elephant. Abstract United States and Canadian Academy of Pathology, , February 28-March 5, 2020.

Li H, Zhang Q, Shuman L, Kaag M, Raman JD2, Merrill S, DeGraff D, Warrick JI, Chen G. Immune Profiles of Invasive Urothelial Carcinoma post Neoadjuvant Therapy and in Positive Lymph Nodes: Parts of the PDL1 Elephant. Abstract United States and Canadian Academy of Pathology, Los Angeles, California, February 28-March 5, 2020.

Mohammad MK, Hu, Y, Chen G, Li, J, Li J. A Truncating Variant of 17-Beta Hydroxysteroid Dehydrogenase13 Protein Protects Against Severe Histopathological Progression of Liver Injury and Cancer Development: Quantitative Next-Generation Sequencing-Based-Analysis and Meta-Analysis. Abstract United States and Canadian Academy of Pathology, Los Angeles, California, February 28-March 5, 2020.

Gvozdjan K., Chen G., Merelo Alcocer V., Yang Z. The detection of braf mutated clone in acute myeloid leukemia with npm1 mutation and extensive extramedullary involvement. Presentation Association for Molecular Pathology, Baltimore, Maryland, November 7-9, 2018.

Warrick JI, Zaleski MP, Gogoj A, Chen G, Raman JD, Kaag MG, Merrill S, Shuman L, Walter V, Kawasawa, FI, DeGraff DJ. Recurrence of Non-Invasive Papillary Urothelial Carcinoma is Associated with Signatures of Cell Cycle Activation and Immune Response. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Merelo Alcocer V., Flamm A., Chen G., Helm K. SOX10 Immunostaining in granulomatous dermatoses and benign reactive lymph nodes. Presentation American Society of Dermatopathology, Chicago, Illinois, November 8-11, 2018.

Li H, Zhang Q, Shuman L, Kaag M, Raman JD2, Merrill S, DeGraff D, Warrick JI, Chen G. Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Warrick JI, Kaag MG, Raman JD, Chan W, Tran T, Kunchala S, DeGraff DJ, Chen G. Morphologic variants of bladder cancer and markers of molecular subtype. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, San Antonio, Texas, March 4-10, 2017.

 

Textbook Chapters:

Mohammad MK, Chen G. Molecular pathology of gastrointestinal tumors. In in Practical Oncologic Molecular Pathology: Frequently Asked Questions. Ding Y, Zhang L, eds. New York, New York: Springer; 2020: In press.

Chen G, Chen E, Li J, Li J, and Lin F. Lower gastrointestinal tract and microsatellite instability (MSI). In Handbook of Practical Immunohistochemistry-Frequently Asked Questions 3rd edition. Lin F, Prichad J, Liu H, WIlkerson M, eds. New York, New York: Springer; 2020: In press.

 

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