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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
BETA-2 GLYCOPROTEIN IGG ANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1841 Geisinger Epic ID: 26879 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 0.5 mL serum. | |
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | |
Specimen stability: |
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months | |
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | |
TEST DETAILS |
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Reference interval: |
Negative <7 U/mL | |
Interpretation guide: |
Negative <7 U/mL Equivocal 7-10 U/mL Positive >10 U/mL |
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CPT code(s): |
86146 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Beta 2 glycoprotein IgG antibody. | |
Methodology: |
Enzyme Immunoassay (EIA) |
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Synonyms: |
B2IGG, Beta 2 Glycoprotein IgG, Beta 2 Glycoprotein IgG AB Anti-B2 glycoprotein; B2 glycoprotein IgG
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Clinical significance: |
A positive beta 2 glycoprotein antibody can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of certain autoimmune thrombotic disorders such as those secondary to systemic lupus erythematosus (SLE) or related antiphospholipid syndrome. Anticardiolipin/beta-2 glycoprotein antibodies must be detected on 2 or more occasions at least 12 weeks apart to fulfill the laboratory diagnostic criteria for Antiphospholipid Syndrome. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC | |
| Review Date: | 12/13/2022 | |