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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
PROTEIN C ANTIGEN |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2933 Geisinger Epic ID: 19492 | |
SPECIMEN COLLECTION |
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Specimen type: |
Plasma (platelet-poor) | |
Preferred collection container: |
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Specimen required: |
1 mL aliquot of plasma; minimum 0.4 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot. | |
Special notes: |
Specimen cannot be collected in sodium citrate tube. See Specimen Processing Instructions. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge within one hour of collection. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. | |
Transport temperature: |
Frozen. Ship frozen sample on dry ice. | |
Specimen stability: |
Room temperature: Unacceptable. Refrigerated: Unacceptable. Frozen (-70°C or lower): 1 year. Frozen (-20°C): 14 days. | |
Rejection criteria: |
Shipping room temperature or refrigerated is unacceptable. Specimen cannot be collected in a 3.8% sodium citrate tube. | |
TEST DETAILS |
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Reference interval: |
70-140% of normal | |
Additional information: |
Limitations: Expected impact by therapeutic levels (potential interference depends upon drug concentration): Warfarin: no effect to decrease; Heparin (UFH or LMWH): no effect; Dabigatran or Argatroban (Thrombin Inhibitors): no effect; Rivaroxaban or Apixaban (Factor Xa Inhibitors): no effect. | |
CPT code(s): |
85302 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Protein C antigen. | |
Methodology: |
Enzyme Immunoassay (EIA) |
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Synonyms: |
PROTCA, Quest test code 19673
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Clinical significance: |
Aids in diagnosis of congenital deficiencies characterized by recurrent venous thrombosis. Acquired deficiencies associated with Protein C include: oral anticoagulant therapy, liver disease, vitamin K deficiency, malignancy, consumptive DIC, surgery, trauma, antibodies to Protein C and hepatic immaturity of the newborn. | |