Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  


Geisinger Epic Procedure Code: LAB2624         Geisinger Epic ID: 23513

Specimen type:
Platelet-free plasma AND serum.
Preferred collection container:
Alternate Collection Container:
Other size blue-top (3.2% sodium citrate) tubes (e.g., 1.8 mL, 4.5 mL)
6 mL red-top (plain, non-serum separator) tube
Specimen required:
Three (3) 1 mL aliquots of platelet-free citrated plasma AND one (1) 1 mL aliquot of serum. Freeze all aliquots.
Special notes:
Collect two (2) 2.7 mL blue-top tubes (3.2% sodium citrate) AND one (1) 6 mL red-top tube (non-serum separator).
Patient preparation:
Must be off heparin 48 hours prior to testing; must be off Coumadin 2 weeks prior to testing.

Specimen processing instructions:
Centrifuge clotted red-top tube for 15 minutes at 2500 x g, 1 mL aliquot serum, and blue-top tubes at the designated speed and time to obtain platelet-poor plasma (< 10,000/uL). Remove plasma and re-spin the plasma for 10 minutes at 3000 rpm. Remove the supernatant platelet free plasma into three (3) 1 mL aliquots, freeze and transport frozen. 
Transport temperature:
Three (3) aliquots of citrated plasma frozen. One (1) aliquot of serum refrigerated.
Specimen stability:
Frozen: -20°C for 30 days, -70°C for 6 months.
Rejection criteria:
Clotted specimen on plasma. Stability limits exceeded.

Reference interval:
See individual test member.
CPT code(s):
85613, 85610, 85730, 86417 x3
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Lupus sensitive APTT (PTT-LA), dilute Russel's viper venom time (DRVVT), beta-2-glycoprotein and anticardiolipin antibodies IgG and IgM. Thrombin time, heparin anti-Xa level, heparin neutralization, LA mixing studies, DRVVT Confirmation and PTT-LA platelet neutralization if indicated.
Mechanical, Chromogenic, and Clot-Based Enzyme Immunoassay (EIA)
LUPACP, Lupus inhibitor, lupus anticoagulant
Clinical significance:
The persistent presence of a lupus anticoagulant in a patient's plasma increases the risk of a thrombotic event. The lupus anticoagulant panel includes a battery of tests to rule out its presence.
Doctoral Director(s:)
Michelle Grant DO    
Review Date: 08/24/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: Coagulation
Technical Lead: Margaret Knowles-Tuchman
Frequency: First shift, twice weekly
Performed STAT? No
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