Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Test Name: Sunquest Test Code Epic Procedure Code Or ID CPT Code:  

LUPUS ANTICOAGULANT PROFILE

ORDERING INFORMATION:
Sunquest Test Code:
LUPACP      Geisinger Epic Procedure Code: LUPACP         Geisinger Epic ID: 23513

SPECIMEN COLLECTION
Specimen type:
Platelet-free plasma AND serum.
Preferred collection container:
Alternate Collection Container:
Other size blue-top (3.2% sodium citrate) tubes (e.g., 1.8 mL, 4.5 mL)
Specimen required:
Three (3) 1 mL aliquots of platelet-free citrated plasma AND one (1) 1 mL aliquot of serum. Freeze all aliquots.
Special notes:
Collect two (2) 2.7 mL blue-top tubes (3.2% sodium citrate) AND one (1) 6 mL red-top tube (non-serum separator).
Patient preparation:
Must be off heparin 48 hours prior to testing; must be off Coumadin 2 weeks prior to testing.

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge clotted red-top tube for 15 minutes at 2500 x g, 1 mL aliquot serum, and blue-top tubes at the designated speed and time to obtain platelet-poor plasma (< 10,000/uL). Remove plasma and re-spin the plasma for 10 minutes at 3000 rpm. Remove the supernatant platelet free plasma into (3) 1 mL aliquots, freeze and transport frozen. 
Transport temperature:
Three (3) aliquots of citrated plasma frozen. One (1) aliquot of serum refrigerated.
Specimen stability:
Frozen: -20°C for 30 days, -70°C for 6 months.
Rejection criteria:
Clotted specimen on plasma. Stability limits exceeded.

TEST DETAILS
Reference interval:
See individual test member.
CPT code(s):
85613, 85610, 85730, 86417 x3
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Prothrombin time, lupus sensitive APTT, dilute Russel's viper venom time, and anticardiolipin antibodies. PT/APTT LA mixing studies, platelet neutralization and beta 2 glycoprotein IgG, IgM and IgA if indicated.
Methodology:
Mechanical Clot-Based
Enzyme-Linked Immunosorbent Assay (ELISA)
Enzymatic Endpoint
Synonyms:
Lupus inhibitor, lupus anticoagulant
Clinical significance:
The persistent presence of a lupus anticoagulant in a patient's plasma increases the risk of a thrombotic event. The lupus anticoagulant panel includes a battery of tests to rule out its presence.
Doctoral Director(s:)
Michelle Grant DO    
Review Date: 04/29/2019

Performing Locations

Geisinger Medical Center

Performing laboratory: Coagulation
Technical Lead: Margaret Knowles-Tuchman
Frequency: First shift, twice weekly
Performed stat? No
Locations  |    Search  |    Site Map |   Contact Us
©2000-2019 Geisinger Health System.   All rights reserved.
*GMC - Geisinger Medical Center; GWV - Geisinger Wyoming Valley Medical Center; GSACH - Geisinger Shamokin Area Community Hospital; GBH - Geisinger Bloomsburg Hospital;
GCMC - Geisinger Community Medical Center (Scranton); GLH - Geisinger Lewistown Hospital; GHS - Geisinger Holy Spirit; GJSH - Geisinger Jersey Shore Hospital,
GSWB - Geisinger South Wilkes-Barre