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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
ANTIPHOSPHOLIPID SYNDROME DIAGNOSTIC PANEL |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1272 Geisinger Epic ID: 53013 | |
SPECIMEN COLLECTION |
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Specimen type: |
Plasma | |
Preferred collection container: |
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Specimen required: |
3 mL plasma; minimum 2 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge light blue-top tube 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice. | |
Transport temperature: |
Frozen. | |
Specimen stability: |
Room temperature: Unacceptable. Refrigerated: Unacceptable. Frozen: 30 days. | |
Rejection criteria: |
Hemolysis • Grossly lipemic • Received room temperature • Received refrigerated • Serum | |
TEST DETAILS |
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CPT code(s): |
85613, 85730, 86146 x3, 86147 x3 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Cardiolipin Antibodies (IgA, IgG, IgM), Beta-2-Glycoprotein I Antibodies (IgG, IgA, IgM), Lupus Anticoagulant Evaluation with Reflex (PTT-LA and dRVVT with Reflex Confirmations). If the PTT-LA test is prolonged (>40 seconds), then Hexagonal Phase Confirm is performed at an additional charge (CPT code(s): 85598). If the Hexagonal Phase Confirm is positive or weakly positive, then a Thrombin Clotting Time will be performed at an additional charge (CPT code(s): 85670). If dRVVT screen is prolonged (>45 seconds), then dRVVT Confirmation will be performed at an additional charge (CPT code(s): 85597). If dRVVT Confirm is positive, then a dRVVT 1:1 Mix will be performed at an additional charge (CPT code(s): 85613). | |
Methodology: |
Photo-Optical Clot Detection Immunoassay |
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Synonyms: |
Quest test code 19872, APhoslip Syn
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Clinical significance: |
This assay may be useful in supporting or ruling out a diagnosis of antiphospholipid syndrome. | |