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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
PHOSPHATIDYLCHOLINE ANTIBODY (IGA) |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1246 Geisinger Epic ID: 52909 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
1 mL serum; minimum 0.5 mL. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and alqiuot. | |
Transport temperature: |
Refrigerated (cold packs). | |
Specimen stability: |
Room temperature: 1 hour. Refrigerated: 14 days. Frozen: 60 days. | |
TEST DETAILS |
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Additional information: |
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means. | |
CPT code(s): |
83520 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Immunoassay |
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Synonyms: |
Quest test code 16679, Ppcholine AB
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Clinical significance: |
Phospholipid autoantibodies specific to phosphatidylinositol (PI), phosphatidylglycerol (PG), phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylcholine (PC), phosphatidic acid (PA), cardiolipin (CL), and sphingomyelin are found in hematologic autoimmune diseases, especially antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). APS is characterized by arterial and venous thrombosis, thrombocytopenia, and recurrent fetal loss; thrombosis, thrombocytopenia, and hemolytic anemia also occur in SLE and are associated with the presence of phospholipid autoantibodies. Women with infertility, showing spontaneous abortion or in vitro fertilization failure, demonstrate PI autoantibodies in 25% of cases. | |