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Geisinger Medical Laboratories Test Catalog
PROSTAGLANDINS D2, SERUM OR PLASMA |
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Geisinger Epic Procedure Code: LAB1127
Geisinger Epic ID: 52433
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SPECIMEN COLLECTION |
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Specimen type: |
Serum (preferred) or plasma | |
Preferred collection container: |
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Alternate Collection Container: |
3 mL lavender-top (K2 EDTA) tube
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Specimen required: |
3 mL serum (preferred) or plasma; minimum 1 mL | |
Special notes: |
Serum or EDTA plasma should be collected and separated as soon as possible. Freeze specimen immediately after separation. | |
Patient preparation: |
Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and aliquot. Freeze specimen immediately after separation. | |
Transport temperature: |
Frozen. | |
Specimen stability: |
Room temperature: Unacceptable. Refrigerated: Unacceptable. Frozen: 30 days. | |
Rejection criteria: |
Room temperature or refrigerated specimen. | |
TEST DETAILS |
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CPT code(s): |
84150 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Radioimmunoassay (RIA) |
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Synonyms: |
Quest test code 63282, Prostaglandi
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Clinical significance: |
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin | |