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Geisinger Medical Laboratories Test Catalog
T-CELL RECEPTOR GAMMA GENE REARRANGE,PCR |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB3120 Geisinger Epic ID: 43719 | |
SPECIMEN COLLECTION |
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Specimen type: |
Whole blood (preferred) or bone marrow aspirate | |
Preferred collection container: |
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Alternate Collection Container: |
3 mL lavender-top (K2 EDTA) tube
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Specimen required: |
5 mL EDTA whole blood, minimum 3mL; or 3 mL bone marrow aspirate, minimum 1 mL | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Room temperature | |
Specimen stability: |
Room temperature: 7 days. Refrigerated: 7 days. | |
TEST DETAILS |
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CPT code(s): |
81342 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Polymerase Chain Reaction (PCR) Fragment Analysis |
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Synonyms: |
Quest test code 90509 T-cell receptor clonality, TCR-gamma clonality TCRGGR
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Clinical significance: |
This assay which interrogates the T-cell receptor gamma locus (TCRG) by a PCR method based on the BIOMED-2 consensus, is useful for establishing clonality of T-cell lymphoid neoplasms and identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a T-cell neoplasm. It can be used in association with the T-cell receptor beta (TCRB) PCR assay (Test code 91446 or TCRG/TCRB combo test code 91445), since false-negative results can occur in up to 5-10% of T-cell malignancies when testing for TCRG PCR only | |