Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

THROMBOSIS PROFILE

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3154         Geisinger Epic ID: 26811

SPECIMEN COLLECTION
Specimen type:
Platelet-free plasma AND serum.
Preferred collection container:
Alternate Collection Container:
4.5 mL blue top (3.2% sodium citrate) tube
Specimen required:
Three (3) 1 mL aliquots of platelet-free citrated plasma , (1) 1 mL aliquot of serum, one (1) 1 mL aliquot of EDTA plasma and one (1) lavender-top EDTA whole blood.
Special notes:
Collect two (2) 2.7 mL blue-top tubes (3.2% sodium citrate) and one (1) 6 mL red-top tube (non-serum separator), and one (2) lavender-top (EDTA) tubes.
Patient preparation:
Patient must be off heparin 48 hours prior to testing; must be off Coumadin 2 weeks prior to testing.

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge one (1) lavender-top tube and clotted red-top tube top for 15 minutes at 2500 x g and blue-top tubes at the designated speed and time to obtain platelet-poor plasma (< 10,000/uL). Remove plasma and re-spin the plasma for 10 minutes at 2500 x g. Remove the supernatant platelet free plasma into three (3) 1 mL aliquots, freeze and transport frozen. 
Transport temperature:
Three (3) aliquots of citrated plasma frozen, one (1) aliquot of serum refrigerated, one aliquot of EDTA plasma frozen, one EDTA lavender whole blood refrigerated.
Specimen stability:
Frozen: -20°C for 30 days, -70°C for 6 months.
Rejection criteria:
Clotted specimen.

TEST DETAILS
Reference interval:
See individual test members.
CPT code(s):
85610, 85730, 85613, 86147 x3,, 85306, 85303, 85307, 85300,, 83090, 85240, 85384
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Prothrombin time, lupus sensitive APTT, Antithrombin, Protein C, Protein S, APC resistance, Homocystein, Anticardiolipin Antibodies, DRVV, Factor VIII, Fibrinogen. Mixing studies, platelet neutralization, and beta 2 glycoprotein if needed. Factor V Leiden and prothrombin gene mutation if needed.
Methodology:
Mechanical Clot-Based
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms:
THRMP, Hypercoagulation panel
Hypercoagulability panel
Thrombophilic panel
Clinical significance:
The thrombosis profile includes all necessary screening and confirmatory (if indicated) tests to rule out if a patient has or is at risk for a hypercoagulable event.
Doctoral Director(s:)
Michelle Grant DO    
Review Date: 04/29/2019

Performing Locations

Geisinger Medical Center

Performing laboratory: Coagulation
Technical Lead: Margaret Knowles-Tuchman
Frequency: First shift, twice weekly
Performed stat? No
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