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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
PORPHOBILINOGEN, QUANTITATIVE, 24-HOUR URINE |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2877 Geisinger Epic ID: 15131 | |
SPECIMEN COLLECTION |
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Specimen type: |
24-hour urine | |
Preferred collection container: |
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Alternate Collection Container: |
24-hour urine collection preserved with 5 g Na2CO3
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Specimen required: |
2 mL aliquot of 24-hour urine collection; minimum 1 mL, protected from light. | |
Special notes: |
Refrigerate during collection and protect from light. Mix well. Estimate total collection volume from 24-hour urine container. Remove required aliquot. Record total volume on both aliquot tube and request slip (if applicable). Wrap tube in aluminum foil or use amber tube to protect from light. | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Refrigerate during and after collection. Protect from light. | |
Specimen stability: |
Room Temperature: Unacceptable. Frozen: 1 month, pH 6-7. Refrigerated: 1week, pH 6-7. | |
Rejection criteria: |
Room temperature specimens unacceptable. Acidified specimens unacceptable. | |
TEST DETAILS |
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Reference interval: |
Porphobilinogen, 24-Hour Urine, For either sex, all ages, 0.0-2.7 mg/24 hr (2.7 mg/24 hr or less) Porphyria Elevated Urine Porphobilinogen* Acute intermittent porphyria + ALA dehydratase deficiency porphyria + Congenital erythropoietic coproporphyia - Erythropoietic protoporphyria - Hepatoerythropoietic porphyria - Hereditary coproporphyria +/- Porphyria cutanea tarda - Variegate porphyria +/- |
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Additional information: |
*Patients with hereditary forms of porphyria usually will present with profound elevations of this analyte (>5-fold) during acute episodes. Moderate elevations (<3-fold) are more often due to medications or environmental factors. | |
CPT code(s): |
84110 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Porphobilinogen, 24 hour urine. | |
Methodology: |
Spectrophotometric (Colorimetric) |
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Synonyms: |
Porphyrin, PORPHO Quest test code 726
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